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These studies were designed to test whether allergens could induce tolerance by altering the allergen structure, the timing of administration or the route of administration, and whether early allergen introduction in at-risk children could prevent future allergies. The goal is to target known allergic pathways in a manner that will facilitate non-inflammatory recognition and processing of antigens to enhance the efficacy and safety of immunotherapy.

The ITN will also continue to explore new allergen preparations and routes of administration to maximize the effectiveness of true tolerogenic protocols. The ITN is also pioneering the in vitro definition of allergen-specific tolerance. As part of this effort the ITN has initiated a set of pilot studies to map detailed, time-dependent immune responses to allergen immunotherapy, as well as to refine methodologies for optimal specimen collection and processing.

toleration on trial

The goal is to use this information to design treatment regimens and clinical studies that better target allergic pathways and promote tolerance. Learn more: Study Summary Clinicaltrials. LEAP Trio will investigate the durability of tolerance to peanut allergen in LEAP participants at age 12, development of peanut allergy in younger siblings of LEAP participants, and parental characteristics that may impact development of food allergy. IMPACT is a clinical research study testing whether daily oral exposure to a peanut product can modify peanut allergy in young children.

Whatsapp Facebook Twitter. Sinopsis Toleration on Trial offers the only multidisciplinary study available on the issue of toleration, bringing together political psychologists, philosophers, sociologists, Islamic scholars, and political theorists to examine the most pressing debates in the field. The volume addresses the toleration question from a number of angles: toleration and its application to gay rights; Islam and toleration; institutional, ideological, and psychological preconditions for its practice; and philosophical and conceptual arguments for the principle of toleration.

The common thread running throughout the volume is the core question: Is toleration primarily a product of institutional arrangements, or is it an attitude of individuals? To answer this adequately, the authors believe that a contemporary analysis of the possibility, significance and requirements of toleration must be fully cognizant of the democratic, or more accurately—politically mobilized—background in which toleration becomes a difficult issue.

Conflicts between deeply divided groups within nations and between groups across political boundaries pose the issue of threat and risk to a practice or way of life that many peoples find difficult to accept.

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Can the idea and practice of toleration manage these in politically and ethically defensible ways? These essays address various aspects of the aim to establish or strengthen toleration among politically mobilized groups, in a context of contemporary democratic challenges. Ver todos.

Click on an option below to access. Log out of ReadCube. Using Morocco as a case study, I claim that interfaith dialogue in the Arab World has largely taken place at elite levels rather than among common people or in schools.

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The Arab political elite has not yet been able to connect the celebrated myth of toleration with the present realities of racism, prejudice and stereotyping to give younger adults a new frame of understanding difference and otherness. Volume 6 , Issue 3. The full text of this article hosted at iucr. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account.

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If the address matches an existing account you will receive an email with instructions to retrieve your username. Aomar Boum University of Arizona Search for more papers by this author. Tools Request permission Export citation Add to favorites Track citation. Share Give access Share full text access. Share full text access. Please review our Terms and Conditions of Use and check box below to share full-text version of article.

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